Synthesized peptide derived from human PDE6D AA range: 89-139
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
分子量:
17kD
基因ID:
5147
蛋白序列:
O43924
细胞定位:
Cytoplasm, cytosol . Cytoplasmic vesicle membrane ; Peripheral membrane protein . Cytoplasm, cytoskeleton, cilium basal body .
研究背景:
This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants. [provided by RefSeq, Mar 2014],