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PDLI2 rabbit pAb
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ES14176
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: PDLI2 rabbit pAb
反应性: Human; Mouse;Rat
别名: PDZ and LIM domain protein 2 (PDZ-LIM protein mystique)
宿主: Rabbit
稀释比: WB 1:500-2000
免疫原: Synthesized peptide derived from human PDLI2 AA range: 190-240
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 38kD
基因ID: 64236
蛋白序列: Q96JY6
细胞定位: Cytoplasm . Nucleus . May be partially nuclear.; [Isoform 1]: Cytoplasm, cytoskeleton. Colocalizes with beta-1 integrin (ITGB1) and alpha-actinin but not with paxillin (PXN).; [Isoform 2]: Cytoplasm, cytoskeleton.; [Isoform 3]: Nucleus.
研究背景: This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011],
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