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PLCγ2 (phospho-Tyr759) rabbit pAb
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ES14068
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: PLCγ2 (phospho-Tyr759) rabbit pAb
反应性: Human;Mouse
别名: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2)
宿主: Rabbit
稀释比: WB 1:500-2000; IF/ICC 1:50-200;ELISA 1:2000-20000;IHC-p 1:50-200
免疫原: Synthesized phosho peptide around human PLCγ2 (Tyr759)
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 148kD
基因ID: 5336
蛋白序列: P16885
细胞定位: intracellular,cytosol,plasma membrane,extracellular exosome,
研究背景: The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014],
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