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S12A1 rabbit pAb
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ES13272
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: S12A1 rabbit pAb
反应性: Human; Mouse;Rat
宿主: Rabbit
稀释比: WB 1：500-2000
免疫原: Synthesized peptide derived from human S12A1 AA range: 595-645
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 121kD
基因ID: 6557
蛋白序列: Q13621
细胞定位: Apical cell membrane ; Multi-pass membrane protein .
研究背景: This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.[provided by RefSeq, May 2010],
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