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SIAH1 rabbit pAb
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ES13109
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: SIAH1 rabbit pAb
反应性: Human;Rat
宿主: Rabbit
稀释比: WB 1：500-2000
免疫原: Synthesized peptide derived from human SIAH1 AA range: 157-207
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 31kD
基因ID: 6477
蛋白序列: Q8IUQ4
细胞定位: Cytoplasm. Nucleus. Predominantly cytoplasmic. Partially nuclear.
研究背景: This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008],
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