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SNX13 rabbit pAb
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ES13032
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: SNX13 rabbit pAb
反应性: Human; Mouse
别名: Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1)
宿主: Rabbit
稀释比: WB 1:500-2000
免疫原: Synthesized peptide derived from human SNX13 AA range: 602-652
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 105kD
基因ID: 23161
蛋白序列: Q9Y5W8
细胞定位: Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side .
研究背景: This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008],
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