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Sox2 (phospho-Ser250/Ser251) rabbit pAb
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ES13010
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Sox2 (phospho-Ser250/Ser251) rabbit pAb
反应性: Human;Mouse
别名: Transcription factor SOX-2
宿主: Rabbit
稀释比: WB 1:500-2000;IHC-p 1:50-300
免疫原: Synthesized phosho peptide around human Sox2 (Ser250 and Ser251)
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 35kD
基因ID: 6657
蛋白序列: P48431
细胞定位: Nucleus speckle . Cytoplasm . Nucleus . Acetylation contributes to its nuclear localization and deacetylation by HDAC3 induces a cytoplasmic delocalization (By similarity). Colocalizes in the nucleus with ZNF208 isoform KRAB-O and tyrosine hydroxylase (TH) (By similarity). Colocalizes with SOX6 in speckles. Colocalizes with CAML in the nucleus (By similarity). Nuclear import is facilitated by XPO4, a protein that usually acts as a nuclear export signal receptor (By similarity). .
研究背景: SRY-box 2(SOX2) Homo sapiens This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008],
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