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TNNC1 rabbit pAb
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ES12618
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: TNNC1 rabbit pAb
反应性: Human; Mouse
宿主: Rabbit
稀释比: WB 1：500-2000
免疫原: Synthesized peptide derived from human TNNC1 AA range: 57-107
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 18kD
基因ID: 7134
蛋白序列: P63316
细胞定位: nucleoplasm,mitochondrion,cytosol,troponin complex,actin cytoskeleton,contractile fiber,
研究背景: Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008],
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