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TYDP1 rabbit pAb
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ES12477
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: TYDP1 rabbit pAb
反应性: Human; Mouse;Rat
宿主: Rabbit
稀释比: WB 1:500-2000
免疫原: Synthesized peptide derived from human TYDP1 AA range: 426-476
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
分子量: 67kD
基因ID: 55775
蛋白序列: Q9NUW8
细胞定位: Nucleus . Cytoplasm .
研究背景: The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). [provided by RefSeq, Aug 2016],
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