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Tyk2 (phospho-Tyr1054/1055) rabbit pAb
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ES12474
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Tyk2 (phospho-Tyr1054/1055) rabbit pAb
反应性: Human;Rat;Mouse;
别名: Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2)
宿主: Rabbit
稀释比: WB 1:1000-2000
免疫原: Synthesized phosho peptide around human Tyk2 (Tyr1054 and 1055)
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 134kD
基因ID: 7297
蛋白序列: P29597
细胞定位: nucleus,cytoplasm,cytosol,cytoskeleton,membrane,extrinsic component of cytoplasmic side of plasma membrane,extracellular exosome,
研究背景: tyrosine kinase 2(TYK2) Homo sapiens This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008],
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