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YB1 (phospho-Ser102) rabbit pAb
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ES12267
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: YB1 (phospho-Ser102) rabbit pAb
反应性: Human;Mouse
别名: Tryptase alpha/beta-1 (Tryptase-1) (EC 3.4.21.59) (Tryptase I) (Tryptase alpha-1)
宿主: Rabbit
稀释比: WB 1:1000-2000
免疫原: Synthesized phosho peptide around human YB1 (Ser102)
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 30kD
基因ID: 7177
蛋白序列: Q15661
细胞定位: Secreted. Released from the secretory granules upon mast cell activation. .
研究背景: Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate gene
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