Synthesized peptide derived from human ZFY27 AA range: 351-401
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
分子量:
45kD
基因ID:
118813
蛋白序列:
Q5T4F4
细胞定位:
Recycling endosome membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cell projection, growth cone membrane ; Multi-pass membrane protein . Localizes at both dendrites and axons (By similarity). Localizes to endoplasmic reticulum tubular network. .
研究背景:
This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear. [provided by RefSeq, Mar 2010],