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RAMP3 rabbit pAb
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ES11934
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: RAMP3 rabbit pAb
反应性: Human;Rat;Mouse;
宿主: Rabbit
稀释比: WB 1:500-2000 ELISA 1:5000-20000
免疫原: Synthesized peptide derived from part region of human protein
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 16kD
基因ID: 10268
蛋白序列: O60896
细胞定位: Cell membrane ; Single-pass type I membrane protein . Membrane ; Single-pass type I membrane protein . Moves from intracellular puncta to the plasma membrane in a RAMP3-dependent manner.
研究背景: The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor. [provided by RefSeq, Jul 2008],
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