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TNR18 rabbit pAb
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ES11808
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: TNR18 rabbit pAb
反应性: Human;Rat;Mouse;
宿主: Rabbit
稀释比: WB 1:500-2000 ELISA 1:5000-20000
免疫原: Synthesized peptide derived from part region of human protein
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 26kD
基因ID: 8784
蛋白序列: Q9Y5U5
细胞定位: [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
研究背景: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011],
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