Synthesized peptide derived from human protein . at AA range: 101-150
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
实测条带:
19kD
基因ID:
345611
蛋白序列:
A1A4Y4
细胞定位:
Golgi apparatus membrane . Cell membrane . Cytoplasmic vesicle, phagosome membrane . Cytoplasmic vesicle, autophagosome membrane . Cell projection, phagocytic cup . Behaves like an integral membrane protein. Recruited to the plasma membrane around forming phagocytic cups, it remains associated with maturing autophagosomes. Preferentially associated with cis- and medial-Golgi. .
研究背景:
immunity related GTPase M(IRGM) Homo sapiens This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis.[provided by RefSeq, Oct 2010],