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Nrf2 (Acetyl Lys599) rabbit pAb
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ES1138
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Nrf2 (Acetyl Lys599) rabbit pAb
反应性: Human;Mouse;Rat
别名: NFE2L2; NRF2; Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/10000. Not yet tested in other applications.
免疫原: Synthesized acetyl-peptide derived from the C-terminal region of human Nrf2 around the acetylation site of K599.
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 75-100kD
基因ID: 4780
蛋白序列: Q16236
细胞定位: Cytoplasm, cytosol . Nucleus . Cytosolic under unstressed conditions: ubiquitinated and degraded by the BCR(KEAP1) E3 ubiquitin ligase complex (PubMed:15601839, PubMed:21196497). Translocates into the nucleus upon induction by electrophilic agents that inactivate the BCR(KEAP1) E3 ubiquitin ligase complex (PubMed:21196497). .
研究背景: This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015],
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