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LECT1 rabbit pAb
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ES11364
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: LECT1 rabbit pAb
反应性: Human;Rat;Mouse
宿主: Rabbit
稀释比: WB 1:500-2000 ELISA 1:5000-20000
免疫原: Synthesized peptide derived from human protein . at AA range: 150-230
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 36kD
基因ID: 11061
蛋白序列: O75829
细胞定位: [Chondromodulin-1]: Secreted, extracellular space, extracellular matrix. Accumulated in the inter-territorial matrix of cartilage.; [Chondrosurfactant protein]: Endomembrane system ; Single-pass membrane protein .
研究背景: This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularizat
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