Synthesized peptide derived from human protein . at AA range: 170-250
储存条件:
-20°C/1 year
克隆性:
Polyclonal
抗体亚型:
IgG
浓度:
1 mg/ml
实测条带:
44kD
基因ID:
59338
蛋白序列:
Q9HB21
细胞定位:
Cytoplasm . Cell membrane ; Peripheral membrane protein. Nucleus . Locates to the plasma membrane after treatments that stimulate the production of PtdIns3,4P2. .
研究背景:
This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Sep 2010],