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TPP1 rabbit pAb
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ES11280
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: TPP1 rabbit pAb
反应性: Human;Rat;Mouse
宿主: Rabbit
稀释比: WB 1:500-2000 ELISA 1:5000-20000
免疫原: Synthesized peptide derived from human protein . at AA range: 10-90
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 61kD
基因ID: 1200
蛋白序列: O14773
细胞定位: Lysosome . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .
研究背景: This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008],
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