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GPNMB rabbit pAb
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ES11148
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: GPNMB rabbit pAb
反应性: Human;Rat;Mouse
宿主: Rabbit
稀释比: WB 1:500-2000 ELISA 1:5000-20000
免疫原: Synthesized peptide derived from part region of human protein
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 62kD
基因ID: 10457
蛋白序列: Q14956
细胞定位: Cell membrane; Single-pass type I membrane protein . Melanosome membrane ; Single-pass type I membrane protein . Early endosome membrane ; Single-pass type I membrane protein . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .
研究背景: glycoprotein nmb(GPNMB) Homo sapiens The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
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