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p73 (Acetyl Lys327) rabbit pAb
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ES1113
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: p73 (Acetyl Lys327) rabbit pAb
反应性: Human;Mouse;Rat
别名: TP73; P73; Tumor protein p73; p53-like transcription factor; p53-related protein
宿主: Rabbit
稀释比: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
免疫原: The antiserum was produced against synthesized Acetyl-peptide derived from human p73 around the Acetylation site of Lys327. AA range:291-340
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 70kD
基因ID: 7161
蛋白序列: O15350
细胞定位: Nucleus . Cytoplasm. Accumulates in the nucleus in response to DNA damage.
研究背景: tumor protein p73(TP73) Homo sapiens This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011],
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