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JAML1 rabbit pAb
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ES10721
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: JAML1 rabbit pAb
反应性: Human;Rat;Mouse;
宿主: Rabbit
稀释比: WB 1:500-2000 ELISA 1:5000-20000
免疫原: Synthesized peptide derived from part region of human protein
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 43kD
基因ID: 120425
蛋白序列: Q86YT9
细胞定位: Cell membrane ; Single-pass type I membrane protein . Cell junction . Localized at the plasma membrane and enriched in areas of cell-cell contacts (PubMed:12869515).
研究背景: domain:The Ig-like V-type domain 2 mediates interaction with CXADR.,function:May function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells.,induction:Up-regulated upon retinoic acid, Me2SO and PMA treatment in differentiating myeloid leukemia cells.,similarity:Belongs to the immunoglobulin superfamily.,similarity:Contains 2 Ig-like V-type (immunoglobulin-like) domains.,subcellular location:Localized at the plasma membrane in areas of cell-cell contacts and at the cell surface of PMN.,subunit:Interacts with CXADR.,tissue specificity:Expression is restricted to the hematopoietic tissues with the exception of liver. Expressed in fetal liver, spleen and thymus.,
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