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DDB2 rabbit pAb
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ES10618
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: DDB2 rabbit pAb
反应性: Human;Mouse
宿主: Rabbit
稀释比: WB 1:500-2000 ELISA 1:5000-20000
免疫原: Synthesized peptide derived from human protein . at AA range: 260-340
储存条件: -20°C/1 year
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1 mg/ml
实测条带: 46kD
基因ID: 1643
蛋白序列: Q92466
细胞定位: Nucleus . Chromosome . Accumulates at sites of DNA damage following UV irradiation. .
研究背景: This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],
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