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phospho-MLKL (S358) (6B4) Mouse mAb
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EM1320
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: phospho-MLKL (S358) (6B4) Mouse mAb
反应性: Human
别名: Mixed lineage kinase domain like protein, FLJ34389
宿主: Mouse
稀释比: IHC 1:100-200
免疫原: Synthetic Peptide
储存条件: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
克隆性: Monoclonal
抗体亚型: IgG1
浓度: 1mg/mL
实测条带: 54kDa
基因ID: 197259
蛋白序列: Q8NB16
细胞定位: Cell membrane, Cytoplasm, Membrane
研究背景: Mixed lineage kinase domain-like protein (MLKL) is a pseudokinase that was identified as downstream target of RIP3 in the necroptosis pathway. During necroptosis RIP3 is phosphorylated at Ser227, which recruits MLKL and leads to its phosphorylation at Thr357 and Ser358.
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