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Cystatin C (7F11) Mouse mAb
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EM1275
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Cystatin C (7F11) Mouse mAb
反应性: Human
别名: AD8, Cystatin3, Gamma trace, HCCAA
宿主: Mouse
稀释比: WB  1:1,000-2,000     IHC 1:100-200     ELISA  1:10,000-20,000
免疫原: Recombinant Protein
储存条件: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
克隆性: Monoclonal
抗体亚型: IgG1
浓度: 1mg/mL
实测条带: 14kDa
基因ID: 1471
蛋白序列: P01034
细胞定位: Secreted
研究背景: Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration, shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus.
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