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CD68 Mouse mAb
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EM1162
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: CD68 Mouse mAb
反应性: Human, Rat, Mouse
别名: CD68 molecule, GP110, Macrosialin, SCARD1
宿主: Mouse
稀释比: IHC 1:200-500
免疫原: Synthetic Peptide
储存条件: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
克隆性: Monoclonal
抗体亚型: IgG1
浓度: 1mg/mL
基因ID: 968
蛋白序列: P34810
细胞定位: Cell membrane and Endosome membrane. Lysosome membrane
研究背景: The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.
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