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EGFR Mouse mAb

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EM1134

规格：	价格：
50µL	￥1280.00
100µL	￥1980.00

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Overview

产品名称:	EGFR Mouse mAb
反应性:	Human
别名:	Epidermal Growth Factor Receptor ;ErbB-1; ErbB1; ER1; ERB-B1; MENA; HER1; Erythroblastic Leukemia Viral(v-Erb-B)oncogene Homolog,Avian; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
宿主:	Mouse
稀释比:	WB 1:1,000-3,000 IP 1:200 IF 1:100-200
免疫原:	Synthetic Peptide
储存条件:	PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
克隆性:	Monoclonal
抗体亚型:	IgG1
浓度:	1mg/mL
实测条带:	170kDa
基因ID:	1956
蛋白序列:	P00533
研究背景:	The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades.

Western blot analysis of 1) A431 ,2) Hela, with EM1134 diluted at 1:2,000.
1、Input: Hela Cell Lysate 2、IP product: IP dilute 1:200 Western blot analysis: primary antibody : EM1134 1:1,000 Secondary antibody: Goat anti-Mouse IgG, Heavy Chain Specific(S003), 1:5,000
IF analysis of Hela with EM1134(Left) and DAPI (Right) diluted at 1:100.

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