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IDE/Insulin Degrading Enzyme Mouse mAb
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EM1083
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: IDE/Insulin Degrading Enzyme Mouse mAb
反应性: Human
别名: Abeta degrading protease, insulin degrading enzyme, Insulin protease, Insulinase, INSULYSIN
宿主: Mouse
稀释比: WB 1:1,000 IHC 1:200
免疫原: Synthetic Peptide
储存条件: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
克隆性: Monoclonal
抗体亚型: IgG1
浓度: 1mg/mL
实测条带: 118kDa
基因ID: 3416
蛋白序列: P14735
细胞定位: Cell membrane, Cytoplasm, Membrane, Secreted
研究背景: Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently.
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