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CA IX/Carbonic Anhydrase IX Mouse mAb
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EM1076
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: CA IX/Carbonic Anhydrase IX Mouse mAb
反应性: Human
别名: CA9, CAIX, Carbonate dehydratase IX, Carbonic anhydrase 9, carbonic anhydrase IX, G250, Membrane antigen MN, MN, P54/58N, pMW1, RCC associated antigen G250
宿主: Mouse
稀释比: WB 1:3,000 IP 1:200  IHC 1:100-200
免疫原: Synthetic Peptide
储存条件: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
克隆性: Monoclonal
抗体亚型: IgG1
浓度: 1mg/mL
实测条带: 35-38kDa
基因ID: 768
蛋白序列: Q16790
细胞定位: Nucleus. Nucleus, nucleolus. Cell membrane. Cell projection, microvillus membrane.
研究背景: The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. CAIX is considered to be one of the best cellular biomarkers of hypoxia. Furthermore, recent studies examining the association between CAIX levels and various clinicopathological outcomes suggest that CAIX expression may also be a valuable prognostic indicator for overall survival. Antibodies against CAIX serve as excellent excellent biomarkers of hypoxic regions in many solid tumors.
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