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FH/Fumarase Mouse mAb
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EM1073
规格: 价格:
50µL ¥1280.00
100µL ¥1980.00

Overview

产品名称: FH/Fumarase Mouse mAb
反应性: Human, Rat, Mouse
别名: Fumarase, fumarate hydratase, HLRCC, LRCC, MCL, MCUL1
宿主: Mouse
稀释比: WB 1:3,000 IF 1:100-200
免疫原: Synthetic Peptide
储存条件: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
克隆性: Monoclonal
抗体亚型: IgG1
浓度: 1mg/mL
实测条带: 50kDa
基因ID: 2271
蛋白序列: P07954
细胞定位: Cytoplasm and Mitochondrion.
研究背景: Fumarase (FH) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate. Fumarase comes in two forms: mitochondrial and cytosolic. The mitochondrial isoenzyme is involved in the Krebs Cycle (also known as the Tricarboxylic Acid Cycle [TCA] or the Citric Acid Cycle), and the cytosolic isoenzyme is involved in the metabolism of amino acids and fumarate. Subcellular localization is established by the presence of a signal sequence on the amino terminus in the mitochondrial form, while subcellular localization in the cytosolic form is established by the absence of the signal sequence found in the mitochondrial variety.
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