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NSE Mouse mAb
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EM1066
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: NSE Mouse mAb
反应性: Human, Rat, Mouse
别名: ENO2, Enolase 2, enolase 2 (gamma, neuronal), Gamma enolase, Neural enolase, Neuron specific enolase
宿主: Mouse
稀释比: WB 1:2,000 IHC 1:200
免疫原: Synthetic Peptide
储存条件: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
克隆性: Monoclonal
抗体亚型: IgG1
浓度: 1mg/mL
实测条带: 47kDa
基因ID: 2026
蛋白序列: P09104
细胞定位: Cytoplasm. Cell membrane.
研究背景: Enolase is a glycolytic enzyme catalyzing the reaction pathway between 2 phospho glycerate and phosphoenol pyruvate. In mammals, enolase molecules are dimers composed of three distinct subunits (alpha, beta and gamma). The alpha subunit is expressed in most tissues and the beta subunit only in muscle. The gamma subunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells. NSE (neuron specific enolase) is found in elevated concentrations in plasma in certain neoplasias. These include pediatric neuroblastoma and small cell lung cancer. Coexpression of NSE and chromogranin A is common in neuroendocrine neoplasms.
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