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CD21 Mouse mAb
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EM1060
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: CD21 Mouse mAb
反应性: Human, Rat, Mouse
别名: C3DR, Complement C3d receptor, Complement receptor type 2, CR2, EBV receptor, Epstein Barr virus receptor, SLEB9
宿主: Mouse
稀释比: IHC 1:200
免疫原: Synthetic Peptide
储存条件: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
克隆性: Monoclonal
抗体亚型: IgG1
浓度: 1mg/mL
实测条带: 113kDa
基因ID: 1380
蛋白序列: P20023
细胞定位: Membrane
研究背景: CD21 also known as complement receptor 2 (CR2), C3d receptor or EBV receptor is a 140 kDa protein. CD21 is a glycosylated type I transmembrane protein consisting of an extracellular face of a series of 15 or 16 CCP domains. CD21 is the receptor for complement components C3d and iC3b as well as the Epstein-Barr virus (EBV) glycoprotein gp350/220. The soluble CD21 (sCD21) was shown to efficiently trigger CD23 signalling pathways in human monocytes. By inducing release of proinflammatory cytokines and upregulating expression of molecules involved in antigen presentation, sCD21 modulates critical monocyte functions that may be relevant to allergic and inflammatory disorders.
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