Glial Fibrillary Acidic Protein ;Intermediate Filament Protein
宿主:
Mouse
稀释比:
WB 1:2,000-5,000 IHC 1:200-500
免疫原:
Synthetic Peptide
储存条件:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
克隆性:
Monoclonal
抗体亚型:
IgG1
浓度:
1mg/mL
实测条带:
45kDa
基因ID:
2670
蛋白序列:
P14136
细胞定位:
Cytoplasm. Associated with intermediate filaments
研究背景:
GFAP is a member of the class III intermediate filament protein family. It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves. In addition, neural stem cells frequently strongly express GFAP. Antibodies to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes.