Caudal Type Homeobox Transcription Factor 2 ;CDX3; Homeobox Protein CDX-2
宿主:
Mouse
稀释比:
WB 1:1,000 IHC 1:200
免疫原:
Synthetic Peptide
储存条件:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
克隆性:
Monoclonal
抗体亚型:
IgG1
浓度:
1mg/mL
实测条带:
42kDa
基因ID:
1045
蛋白序列:
Q99626
细胞定位:
Nucleus
研究背景:
CDX2 is a caudal type homeobox gene that encodes an intestine-specific transcription factor that is expressed early in intestinal development and may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior marker compared to CK20.