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CK16 Mouse mAb
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EM1056
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: CK16 Mouse mAb
反应性: Human, Rat, Mouse
别名: Cytokeratin 16, K16, K1CP, keratin 16, KRT16, KRT16A, NEPPK
宿主: Mouse
稀释比: IHC 1:200
免疫原: Synthetic Peptide
储存条件: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
克隆性: Monoclonal
抗体亚型: IgG1
浓度: 1mg/mL
实测条带: 51kDa
基因ID: 3868
蛋白序列: P08779
细胞定位: Intermediate filament
研究背景: Keratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating.
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