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Bcl-2 Mouse mAb
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EM1041
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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产品名称: Bcl-2 Mouse mAb
反应性: Human, Rat, Mouse
别名: B-Cell Leukemia/Lymphoma 2 ;B-Cell CLL/Lymphoma 2
宿主: Mouse
稀释比: WB 1:1,000-2,000 IHC 1:200 IF 1:100-200
免疫原: Synthetic Peptide
储存条件: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
克隆性: Monoclonal
抗体亚型: IgG1
浓度: 1mg/mL
实测条带: 26kDa
基因ID: 596
蛋白序列: P10415
细胞定位: Mitochondrion outer membrane,Nucleus membrane,Endoplasmic reticulum membrane
研究背景: BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability.
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