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PCNA Mouse mAb
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EM1030
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview 文献(1)

产品名称: PCNA Mouse mAb
反应性: Human, Rat, Mouse
宿主: Mouse
稀释比: WB 1:5,000 IHC 1:200
免疫原: Synthetic Peptide
储存条件: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
克隆性: Monoclonal
抗体亚型: IgG1
浓度: 1mg/mL
实测条带: 29kDa
基因ID: 5111
蛋白序列: P12004
细胞定位: Nucleus
研究背景: PCNA is a marker for cells in early G1 phase and S phase of the cell cycle. It is found in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6 dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for PCNA. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
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