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Kininogen 1 Rabbit pAb
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EA367
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: Kininogen 1 Rabbit pAb
反应性: Human, Mouse, Rat
别名: BDK, Fitzgerald factor, HMWK, Ile Ser Bradykinin Bradykinin, Kallidin I Lysyl bradykinin, kininogen 1, KNG, KNG1
宿主: Rabbit
稀释比: WB 1:1500-1,000  IHC 1:100-200
免疫原: Recombinant Protein
储存条件: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1mg/mL
实测条带: 45-120kDa
基因ID: 3827
蛋白序列: P01042
细胞定位: Secreted
研究背景: Kininogens are inhibitors of thiol proteases;  HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes;  the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects. LMW-kininogen inhibits the aggregation of thrombocytes;  LMW-kininogen is in contrast to HMW-kininogen not involved in blood clottingUCHL1, UCHL3, UCHL5/UCH37, and BRCA-1-associated protein-1 (BAP1) belong to the UCH family of DUBs, which all posses a conserved catalytic domain (UCH domain) of about 230 amino acids.  UCHL1 is abundantly expressed in neuronal tissues and testes.
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