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CD10 Rabbit pAb
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EA321
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

产品名称: CD10 Rabbit pAb
反应性: Human, Rat, Mouse
别名: CALLA, Enkephalinase,MME,NEP, Neutral endopeptidase antibody
宿主: Rabbit
稀释比: IHC 1:200-500
免疫原: Recombinant Protein
储存条件: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1mg/mL
实测条带: 85kDa
基因ID: 4311
蛋白序列: P08473
细胞定位: Cell membrane
研究背景: CD10 is a zinc-dependent metalloprotease enzyme that degrades a number of small secreted peptides, most notably the amyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimer's disease. Synthesized as a membrane-bound protein, the neprilysin ectodomain is released into the extracellular domain after it has been transported from the Golgi apparatus to the cell surface. In neurons, neprilysin is regulated by the protein nicastrin, a component of the gamma secretase complex that performs a necessary step in processing amyloid precursor protein to amyloid beta.
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