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VEGF Rabbit pAb
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EA320
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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产品名称: VEGF Rabbit pAb
反应性: Human, Rat, Mouse
别名: VEGFA antibody, VPF antibody, VEGF120 antibody, Vascular endothelial growth factor antibody
宿主: Rabbit
稀释比: IHC 1:200-500
免疫原: Recombinant Protein
储存条件: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
克隆性: Polyclonal
抗体亚型: IgG
浓度: 1mg/mL
实测条带: 23,45kDa
基因ID: 7422
蛋白序列: P15692
细胞定位: Secreted
研究背景: VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are associated with microvascular complications of diabetes type 1 (MVCD1). VEGFA has 17 isoforms with MW from 16 to 45 kDa. Some isoforms have homodimer forms (e.g.; VEGFA189 38kDa or VEFGA110 34kDa). VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids (PMID:15602010 ). This antibody can recognize all VEGFA isoforms.
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