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Choactase rabbit pAb
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ES1975
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

Product name: Choactase rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: CHAT; Choline O-acetyltransferase; CHOACTase; ChAT; Choline acetylase
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Choactase. AA range:334-383
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 82,70kD
GeneID: 1103
Human Swiss-Prot No: P28329
Cellular localization: nucleus,cytoplasm,cytosol,presynapse,
Background: This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform. [provided by RefSeq, May 2010],
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