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MOR-1 (phospho Ser375) rabbit pAb
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ES1525
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

Product name: MOR-1 (phospho Ser375) rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: OPRM1; MOR1; Mu-type opioid receptor; M-OR-1; MOR-1; Mu opiate receptor; Mu opioid receptor; MOP; hMOP
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Opioid Receptor around the phosphorylation site of Ser375. AA range:341-390
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 45kD
GeneID: 4988
Human Swiss-Prot No: P35372
Cellular localization: Cell membrane ; Multi-pass membrane protein . Cell projection, axon . Perikaryon . Cell projection, dendrite . Endosome . Is rapidly internalized after agonist binding. .; [Isoform 12]: Cytoplasm .
Background: This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains. [provided by RefSeq, Oct 2013],
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