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Cleaved-Caspase-2 p18 (G170) rabbit pAb
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ES1016
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview

Product name: Cleaved-Caspase-2 p18 (G170) rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: CASP2; ICH1; NEDD2; Caspase-2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Caspase 2 p18 N-ternal. AA range:151-200
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 18 or 35kD
GeneID: 835
Human Swiss-Prot No: P42575
Cellular localization: nucleus,cytoplasm,mitochondrion,cytosol,membrane,
Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011],
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