PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality:
Monoclonal
Isotype:
IgG1
Concentration:
1mg/mL
Observed Band:
17,25kDa
GeneID:
7124
Human Swiss-Prot No:
P01375
Cellular localization:
Secreted,Cell membrane
Background:
TNF-α, the prototypical member of the TNF protein superfamily, is a homotrimeric type-II membrane protein. It can cause cytolysis of certain tumor cell lines; it is involved in the induction of cachexia; it is a potent pyrogen, causing fever by direct action or by stimulation of interlerukin-1 secretion; it can stimulate cell proliferation and induce cell differentiation under certain conditions..