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β-Catenin Rabbit pAb
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EA147
规格： 价格：
50µL ￥1280.00
100µL ￥1980.00
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Overview 文献(1)

Product name: β-Catenin Rabbit pAb
Reactivity: Mouse, Rat
Alternative Names: beta catenin, b-catenin, CTNB1, CTNNB1, FLJ25606, OTTHUMP00000162082
Source: Rabbit
Dilutions: WB 1:1,000  IHC 1:500-1,000
Immunogen: Recombinant Protein
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Clonality: Polyclonal
Isotype: IgG
Concentration: 1mg/mL
Observed Band: 92kDa
GeneID: 1499
Human Swiss-Prot No: P35222
Cellular localization: Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane, Nucleus, Synapse
Background: The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development.
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